Q熱IgM（一、二階段）免疫熒光玻片試劑盒

Coxiella burnetii IgM IFA Kit

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Q熱IgM（一、二階段）免疫熒光玻片試劑盒

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【公司名稱】 廣州健侖生物科技有限公司
【】    楊永漢 
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斯特凡·黑爾：挑戰(zhàn)百年既定法則
自1990年獲得海德堡大學博士學位后，斯特凡·黑爾一直在尋找一種方法，希望能繞開阿貝定義了一個多世紀的衍射極限。挑戰(zhàn)一個既定法則的想法是誘人的，但他的熱情遭到了德國*科學家的質(zhì)疑，因此，黑爾躲到了芬蘭，圖爾庫大學一位研究熒光顯微鏡的教授將他納入了自己的研究團隊。
所謂熒光顯微鏡，就是一種利用熒光分子，比如可與特定細胞DNA(脫氧核糖核酸)耦合的熒光抗體，來對細胞的某個部分成像的技術(shù)。如果抗體與DNA耦合，它們會在細胞的中心發(fā)光。這種方法可讓科學家看到特定分子所處的位置，但他們找到的是一團分子，比如糾纏的DNA的鏈，過低的分辨率使他們無法分清單個的DNA鏈。
1993年，當黑爾在翻閱一本量子光學教科書上有關(guān)受激發(fā)射的內(nèi)容時，突然靈光乍現(xiàn)——受激發(fā)射可以讓熒光分子“熄滅”。1994年，黑爾發(fā)表文章闡述了自己的想法。他提出了所謂的受激發(fā)射損耗(STED)方法：利用一束光脈沖激發(fā)的所有熒光分子，而另一束光脈沖“熄滅”熒光，但每次保留一部分體積約納米大小分子發(fā)著光。用這樣一個納米“手電筒”沿著樣品掃描并連續(xù)地測量光強度，就能夠獲得一張綜合的圖像。每次掃描時保留的熒光分子體積越小，zui終圖像的分辨率就越高，因此，從理論上來說，光學顯微鏡的分辨率再無任何限制了。

Stefan Hale: challenge a hundred years of established law
Stephane Hale has been searching for a way since he received his Ph.D. from Heidelberg University in 1990, hoping to circumvent Abe defining the diffraction limit of more than a century. The idea of ??challenging an established law was tempting, but his passion was questioned by German veteran scientists, so Hale hid in Finland and a professor at Fluke University studying fluorescence microscopy included him in his research team .
A so-called fluorescent microscope is a technique that uses a fluorescent molecule, such as a fluorescent antibody that can be coupled to a specific cellular DNA (DNA), to image a part of a cell. If antibodies are coupled to DNA, they will glow in the center of the cell. This method allows scientists to see where specific molecules are located, but they find a group of molecules, such as entangled DNA chains, whose low resolution prevents them from differentiating between individual DNA strands.
In 1993, when Hale glanced through a Quantum Optics textbook about stimulated emission, suddenly Emmanuel emerged - stimulated emission can make fluorescent molecules "extinguished." In 1994, Hale published an article describing her own ideas. He proposed the so-called stimulated emission loss (STED) method: using one pulse of light to excite all fluorescent molecules, while the other burst of light "extinguished" fluorescence, but each time a fraction of the nanometer-sized molecules remain in the volume of light. With such a nano "flashlight" along the sample scan and continuous measurement of light intensity, you can get a comprehensive image. The smaller the volume of fluorescent molecules retained per scan, the higher the resolution of the final image, so theoretically there is no limit to the resolution of the optical microscope.